"Treatment of Later Humoral Rejection with Anti-CD20 Monoclonal Antibod" by Helen Hayes, Clare Wood et al.
 

Abstract

Humoral or vascular rejection is a B cell-mediated production of immunoglobulin (Ig) G antibody against a transplanted organ that results in immune complex deposition on the vascular endothelium, activation of the complement cascade, production of endothelial dysfunction and regional ischaemic injury.

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