Publication Details
Yang, Y.,
Shi, Y.,
Zhang, N.,
Wang, S.,
Ungvari, G.,
Ng, C.,
Wang, Y.,
Zhao, X.,
Wang, Y.,
Wang, C.,
&
Xiang, Y.
(2016).
The disability rate of 5-year post-stroke and its correlation factors: A national survey in China.
PLoS One, 11 (11).
Abstract
Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors. A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity, depression, cognitive impairment, stroke recurrence and physical disability. Disability was assessed with the modified Ranking Score (mRS), of which a cutoff score _2 indicates disability. Statistical analysis included chi-square tests, two independent samples t-tests, Mann-Whitney U test and multiple logistic regression analysis. The frequency of disability in this study population was 45%. Multivariate analyses revealed that older age, lower education level, previous history of stroke, stroke severity at admission, depression, cognitive impairment at 3 months, and stroke recurrence within 5 years follow up were all significantly associated with post-stroke disability. The disability rate in 5-year post-stroke was high in Chinese patients. Treatment of depression, se
Keywords
stroke, cognitive impairment, depression, China, demography, ischemic stroke
Link to Publisher Version (URL)
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165341