Cyclical variation in the incidence of childhood type 1 diabetes in Western Australia (1985–2010)

Authors

Aveni Haynes
Max K. Bulsara, University of Notre Dame AustraliaFollow
Carol Bower
Timothy W. Jones
Elizabeth A. Davis

Publication Details

Haynes, A., Bulsara, M. K., Bower, C., Jones, T. W., & Davis, E. A. (2012). Cyclical variation in the incidence of childhood Type 1 Diabetes in Western Australia (1985–2010). Diabetes Care, Online First. doi:10.2337/dc12-0205

Abstract

Objective: To examine the incidence of childhood type 1 diabetes in Western Australia from 1985–2010.

Research Design and Methods: Incidence rates were calculated for children aged 0–14 years and were analyzed by calendar year, sex, and age at diagnosis.

Results: There were 1,873 cases, and the mean incidence was 18.1/100,000 person-years (95% CI: 17.5–19.2). The incidence increased by 2.3% a year (1.6–2.9%) with a sinusoidal 5-year cyclical variation of 14% (7–22%). The lowest rate of increase in incidence was observed in 0–4-year-olds.

Conclusions: The cyclical pattern in incidence observed supports the role of environmental factors in childhood type 1 diabetes.

Keywords

peer-reviewed