Background: Comorbid depression in Hepatitis B virus (HBV) is common. Developing accurate and time efficient tools to measure depressive symptoms in HBV is important for research and clinical practice in China.

Aims: This study tested the psychometric properties of the Chinese version of the 16-item Quick Inventory of Depressive Symptomatology (QIDS-SR) in HBV patients.

Methods: The study recruited 245 depressed patients with HBV and related liver disease. The severity of depressive symptoms was assessed with the Montgomery-Asberg Depression Rating Scale (MADRS) and the QIDS-SR.

Results: Internal consistency (Cronbach’s alpha) was 0.796 for QIDS-SR. The QIDS-SR total score was significantly correlated with the MADRS total score (r=0.698, p.

Conclusions: The QIDS-SR (Chinese version) has good psychometric properties in HBV patients and appears to be useful in assessing depression in clinical settings.


depressive symptoms, psychometric properties, QIDS-SR, Hepatitis B Virus


Final version archived in Research Online in accordance with the Shanghai Archives of Psychiatry’s open access repository policy.

Available: http://www.shanghaiarchivesofpsychiatry.org/AboutUs.aspx

Copyright is reserved to the Editorial Department of Shanghai Archives of Psychiatry.

Find in your library