Rushworth, R. L.,
Munns, C. F.,
Maguire, A. M.,
Torpy, D. J.
Hospital admission patterns in children with CAH: admission rates and adrenal crises decline with age.
International Journal of Endocrinology, 2016.
Objective: To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH).
Design: A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia.
Patients: All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI).
Main Outcome Measures: Admissions and comorbidities by age and sex.
Results: Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% (𝑛 = 249) of the CAH patient admissions and 51.7% (𝑛 = 1613) of the non-AI group, 𝑝 < 0.001. Children aged up to one year had the highest number of admissions (𝑛 = 149) and six ACs (four in males).There were 21 ACs recorded for children aged 1–5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. Conclusions. Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.
Congenital Adrenal Hyperplasia (CAH), hospitalisation, hospital admission, gender, age