Article Title

Child psychopharmacology, effect sizes, and the big bang


To the Editor: We read with interest the article by Karen Dineen Wagner, M.D., Ph.D., et al. (1) in the June issue. In their study comparing citalopram to placebo, we were surprised to find the authors reporting an overall effect size of 2.9. With the commonly cited criteria set forth by Cohen, effect sizes can be considered trivial (<0.2), small (0.2 to <0.5), moderate (0.5 to 0.8), or large (>0.80).