Characteristics of the arthropathy described in hereditary haemochromatosis
Publication Details
Carroll, G. J., Breidahl, W. H., & Olynyk, J. K. (2011). Characteristics of the arthropathy described in hereditary haemochromatosis. Arthritis Care and Research, Online First. doi:10.1002/acr.20501
Abstract
Hereditary Haemochromatosis is a common inherited disorder, which primarily affects populations of northern European origin. Individuals homozygous for the C282Y mutation in the HFE gene product have up to a 30 percent chance of developing significant disease as a result of iron overload. Arthropathy is arguably the most disabling complication of iron overload in this disorder. Here we review the clinical and pathophysiological aspects of arthropathy in Hereditary Haemochromatosis.
Keywords
peer-reviewed
