Rushworth, R. L.,
Torpy, D. J.,
New England Journal of Medicine, 381, 852-861.
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients. Adrenal crisis appears to be increasing in frequency, despite the availability of effective preventive strategies. This review examines the definitions, pathophysiology, epidemiology, and treatment of adrenal crises.
adrenal crises, definitions, pathophysiology, epidemiology, treatment