Di Pietro, F., Stanton, T. R., Parkitny, L., McCauley, J. H., Lotze, M., Wand, B. M., & Moseley, G. L. (2012). Functional changes in the primary somatosensory cortex in complex regional pain syndrome (CRPS): A systematic review. 14th World Congress on Pain.
The brain plays a key role in CRPS. A widely-studied brain region in pain research is the primary somatosensory cortex (S1), a somatotopic map of our body’s surface which functionally reorganises in pain . Changes in the S1 representation of the CRPS-affected body part have contributed to new CRPS treatments, e.g. graded motor imagery. This systematic review and meta-analysis aimed to determine whether CRPS is associated with: a) a change in the size of the S1 representation of the affected body part; b) altered S1 activity, in terms of activation levels and latency of responses.
Poster Abstract presentation