Pancreatic MAP kinase pathways and acetaldehyde
Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology. [From publisher's website]
Apte, M., McCarroll, J., Pirola, R., & Wilson, J. (2007). Pancreatic MAP kinase pathways and acetaldehyde. In D. J. Chadwick & J. Goode (Eds.), Acetaldehyde-related pathology: Bridging the trans-disciplinary divide (pp. 200-210). United Kingdom: Wiley.