Abstract

Objective: To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH).

Design: A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia.

Patients: All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI).

Main Outcome Measures: Admissions and comorbidities by age and sex.

Results: Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% (𝑛 = 249) of the CAH patient admissions and 51.7% (𝑛 = 1613) of the non-AI group, 𝑝 < 0.001. Children aged up to one year had the highest number of admissions (𝑛 = 149) and six ACs (four in males).There were 21 ACs recorded for children aged 1–5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. Conclusions. Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.

Keywords

Congenital Adrenal Hyperplasia (CAH), hospitalisation, hospital admission, gender, age

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Link to Publisher Version (DOI)

http://doi.org/10.1155/2016/5748264