Article Title

Characteristics of the arthropathy described in hereditary haemochromatosis

Abstract

Hereditary Haemochromatosis is a common inherited disorder, which primarily affects populations of northern European origin. Individuals homozygous for the C282Y mutation in the HFE gene product have up to a 30 percent chance of developing significant disease as a result of iron overload. Arthropathy is arguably the most disabling complication of iron overload in this disorder. Here we review the clinical and pathophysiological aspects of arthropathy in Hereditary Haemochromatosis.

Keywords

peer-reviewed

 

Link to Publisher Version (DOI)

http://doi.org/10.1002/acr.20501