Title

Increase in circadian variation after continuous-flow ventricular assist device implantation

Document Type

Article

Publication Date

2010

Abstract

The circadian rhythm of varying blood pressure and heart rate is attenuated or absent in patients with severe heart failure. In 28 patients supported by a left ventricular assist device (LVAD) for at least 30 days, a restoration of the circadian rhythm was demonstrated by a consistent nocturnal decrease, and then increase, of the LVAD flow while at a constant LVAD speed. The return of the circadian rhythm has implications for cardiac recovery, and the observation indicates that the continuous-flow LVAD has an intrinsic automatic response to physiologic demands.

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This article may be accessed from the publisher here

The Journal of Heart and Lung Transplantation may be accessed from the National Library of Australia here


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